-
Michael J. Fox Foundation Awards $1.5 Million to Further Drug Development and Discovery Effort in Parkinson's
August 12, 2005
… for Parkinson’s Research (MJFF) has awarded $1.5 million to fund seven projects that each aim to validate therapeutic … is a key step in the drug discovery process that employs compound screens and animal models to determine whether a … of promising therapeutic targets for Parkinson’s disease; however neither academics nor industry has devoted …
-
Episode 29: Developing a Novel App to Improve Speech Intelligibility in Parkinson's Disease with Dr. Gemma Moya-Galé
December 17, 2024
… Parkinson's disease significantly impacts various aspects of communication, and this can make it challenging for people with the disease to communicate effectively, be understood by others, and … J. Fox Foundation, to help people with Parkinson’s improve how well their speech is understood. The app uses …
-
Delivery of GDNF to the Brain by Novel Nanovesicles for the Treatment of Parkinson’s Disease (Supplement)
… upon the research from a prior grant: Delivery of GDNF to the Brain by Novel Nanovesicles for the Treatment of PD Promising Outcomes of Original Grant: The overall goal of this project is … models and, during the selected treatment regimen, measured how this treatment affects (improves) the rotation behavior. …
-
Using "Big Data" Methods to Better Plan Clinical Trials and Predict Outcomes of Parkinson's Disease
… in every case, which makes reliable prediction of future outcomes challenging. Looking for better ways to predict disease progression, researchers have been trying … people whose disease has been progressing similarly. However, most of these studies did not use the “big data” …
-
“Back to the Future” Stars and Team Fox Unite for Movie-Inspired Week-Long Fundraiser
June 29, 2016
… Back to the Future (BTTF) fans and the Parkinson’s community … donated $5,000 to the Foundation. All said, this unforgettable week raised nearly $44,000 for Team Fox! Read …
-
Toll-like Receptor Inhibition to Block Alpha-synuclein-induced Pro-inflammatory Signaling and Cytokine Release
… by alpha-synuclein protein-containing aggregates. Toll-like receptors (TLRs), which includes TLR2, play a … signaling. Recently, alpha-synuclein aggregates have been shown to activate adverse inflammation signaling in the CNS. … will facilitate confirmation of mechanism of action and target engagement to aid clinical hypothesis testing. …