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Interplay Between Microtubules, Alpha-synuclein and Inflammation as a Clue to Understanding and Managing Parkinson’s Disease
… formation of synapses, structures through which brain cells communicate. Microtubule dysfunction leads to a loss of synapses and, as a result, negatively affects the function of brain cells. While … Access to Data and Biospecimens …
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Michael J. Fox Foundation Awards $1.9 Million to Support Ceregene Phase Ii Gene Therapy Clinical Trial
October 10, 2006
… for Parkinson’s Research (MJFF) will provide $1.9 million to support Ceregene Inc.’s Phase II study of CERE-120. This … neurturin, a potent nervous system trophic factor, has shown potential in preclinical studies to slow or stop … neuroprotective effect in patients. The MJFF funding complements Ceregene’s own multi-million dollar investment …
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Get Moving with Ellen Maguire
November 19, 2013
… living with Parkinson’s disease share their passion and how this activity is improving their outlook. Ellen Maguire … glass from old windows I’ve salvaged. It brings me such joy to see the light shining through a piece I’ve created and to … my quality of life and provides me with such a feeling of accomplishment. As with anything, I’ve learned to organize it …
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How One Social Media Post Led to a Massive Crowdsourcing Campaign for Parkinson’s Patients
January 13, 2021
… In our world today, social media is ubiquitous. We turn to Facebook, … life, at home, and when we’re looking for entertainment. However, less obvious is the role played by … to grab his medication from a bottle. Members of the TikTok community — many of whom have no personal connection to PD …
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Coast to Coast: A 50-hour, 2,400-Mile Journey in Support of Team Fox
October 6, 2014
… Andrew Westland prepare for their cross country journey. Tomorrow morning, Team Fox member Bob Kuhn will set out to complete the 50-hr, 2,400-mile motorcycle journey from … Parkinson’s in January 2006, Bob’s coast-to-coast ride is a testament to his determination not to let the disease set …
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Development of Analytic Tests to Use as Nilotinib Companion Diagnostics in Parkinson's Disease
… activity of the c-abl protein in the brain may contribute to the development and progression of Parkinson's disease … (PD). Nilotinib, a drug that inhibits c-abl, has recently shown promise as a potential therapeutic. In its activated … clinical trials, and, in the future, these assays could become a companion diagnostic for the drug. The tests we …