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Developing a Binding Assay to Detect Toxic Alpha-synuclein Aggregates in Cerebrospinal Fluid and Plasma
… Study Rationale: The formation of toxic protein aggregates is an early step in the pathology … disorders, including Parkinson’s disease (PD). Using computer simulations, we discovered that these toxic … (PD). This unusual structure represents an attractive target for the early detection of disease and the development …
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Assessing Genetic Predisposition to Gastrointestinal Symptoms in Young-onset and Late-onset Parkinson’s Disease
… Study Rationale: Constipation is a common, nonmotor manifestation of Parkinson’s disease (PD) that can … about the genetic predisposition to developing gastrointestinal symptoms in patients with young-onset and … Autonomic Dysfunction …
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Fox Trial Finder, Web-Based Clinical Trial Matcher to Accelerate Parkinson's Research, Launched by Michael J. Fox Foundation
April 24, 2012
… informed about clinical trials 61% of patients don’t know where to obtain information about trials 77% of patients … new trials launch, without you having to come back to the site to search again.” Overcoming Misperceptions and a Lack … a profile and start finding potential trial matches today, visit www.foxtrialfinder.org . About The Michael J. Fox …
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Testing Biofluid Samples from the Arizona Study of Aging and Neurodegenerative Disorders for Alpha-synuclein and Biomarkers of Alzheimer’s Disease
… and Neurodegenerative Disorders (AZSAND) has amassed a comprehensive collection of samples and longitudinal clinicopathological data. In this … of this resource to test cerebrospinal fluid (CSF) samples for alpha-synuclein using Amprion’s synuclein seed …
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Michael J. Fox Foundation Announces “Team Fox Challenge”: A Program to Inspire Increased Participation in Community Fundraising for Parkinson’s Research
October 7, 2008
… Foundation has announced the Team Fox Challenge , a program to inspire increased participation in Team Fox, MJFF’s national grassroots community fundraising program. The challenge has been made … “When Michael started the Foundation, we had no concept of how powerful a grassroots movement could be in our funding …
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The Michael J. Fox Foundation Funds Three Research Teams to Seek Common Biological Pathways Underpinning Environment, Genetics and Aging in Parkinson's Onset and Progression
March 22, 2018
… $6-million, two-year program to holistically investigate known risk and causal factors toward discovery of common framework underlying onset and progression of … of what Parkinson's is -- so that we can better strategize how to slow or stop the disease." A Holistic Approach …