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New Study Reports Levodopa Better than Other Drugs in the Long-term
June 11, 2014
… Whether to begin Parkinson’s treatment with the gold-standard levodopa or other therapy (e.g., dopamine agonist, MAO-B inhibitor) is a … and led by Dr. Richard Gray of the University of Oxford compared the three therapies in a total of 1,620 newly …
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Monocyte Monitoring in LRRK2-associated Parkinson’s Disease
… clinical setting. Project Description: Within this project researchers will use a colony-forming cell (CFC) assay to … potentially relevant effects for PD treatment. Relevance to Diagnosis/Treatment of Parkinson’s Disease: By applying the … they believe that the CFC assay is a suitable tool for early diagnosis of LRRK2-associated PD. Anticipated …
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Improving the generalizability and robustness of MRI-derived biomarkers of Parkinson's Disease through analytical and data variability evaluations
… Medical imaging is a promising technique to help with the early diagnosis, understanding, and treatment of Parkinson's … advanced image acquisition techniques and software tools, researchers can derive insightful measurements from such …
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Changes in Mitochondrial DNA as Diagnostic and Progression Biomarkers of Parkinson's Disease
… inside each of the mitochondria. These changes could aid in diagnosis and prognosis by serving as a signal of disease or … 10 people with the slowest disease progression. Impact on Diagnosis/Treatment of Parkinson's disease: Firstly, biomarkers based on mtDNA methylation will aid in early diagnosis of PD. These biomarkers will also make …
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Development of Selective Markers for Imaging Abnormal Protein Aggregates in Parkinson’s Disease
… serve as attractive targets for therapeutics and disease diagnosis. To enable these applications, a noninvasive … altered forms of alpha-synuclein or tau. Impact on Diagnosis/Treatment of Parkinson’s Disease: PET tracers that … in PD and related neurodegenerative disorders, would enable early diagnosis, the monitoring of disease progression and …
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7 Tips for New Parkinson's Disease Caregivers
November 20, 2014
… the following advice from our Facebook community on the early days, weeks and months of a diagnosis can offer guidance. Please add your tips as well. … can be a natural response to a challenging disease, researchers believe that it can also be a Parkinson's …