… a prior grant: The role of TNF-mediated dopaminergic neurotoxicity in Parkinson's disease: Novel anti-TNF biologics as … ways to further pursue this promising avenue. Final Outcome The studies funded by the second supplement … inviting us to submit a proposal to validate TNF as a target in a pre-clinical model of HD in 2008. Technical …

… disease (PD). We have found that these mutations disrupt autophagy—a process that cells deploy to degrade intracellular … and misfolded proteins. In this study, we will investigate how LRRK2 mutations impair autophagy and assess how defects … resulting in the buildup of toxic protein clumps. Comparing the results from mouse and human neurons will …

… 10, a dozen runners living with Parkinson’s disease (PD) completed one of the longest and most grueling relay races … more than 200 mountainous miles from southwestern Virginia to North Carolina, with up to 17,000-foot elevations and a … all pushing each other to continue. I can't even describe how grateful I am that I went through with it.”  Beyond the …

… the estimated 110,000 veterans with PD in the United States today, often have similar questions throughout their disease … questions. Leading research has demonstrated that a combination of factors including lifestyle, environment and … long time. Life has a lot of storms, so you’ve got to learn how to dance in the rain.” Looking for more resources …

… Gene Therapy for Parkinson's Disease Promising Outcomes of Original Grant: Recombinant plasmid DNA encoding for glial cell line-derived neurotrophic factor (GDNF) was compacted into nanoparticles, injected safely … overexpress GDNF in the striatum, which has been shown to be therapeutic in patients suffering from …

… over the past few weeks, and she thinks there’s more to say. She read our post on this topic with interest and felt compelled to share her point of view. What do you think? … trials. 3.  Discouraging current and future investors. How we deal with failure and success can make or break not …