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Study on Rate of Dopamine Loss Emphasizes Need for Biomarkers
October 7, 2013
… for biomarkers for earlier detection, encourages concerted research efforts to advance understanding of dopamine loss … a study supported by The Michael J. Fox Foundation (MJFF), researchers found that dopamine activity in one part of the brain is significantly depleted four years after PD diagnosis. “We found that degeneration took place much …
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Autonomic Profiles of LRRK2 Mutation Carriers with Parkinson’s Disease and Non-manifesting, First-degree Relatives
… the findings, we will assess the integrity of nerves going into the heart in a subset of non-manifesting and … and cardiac nerve integrity will be explored. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Autonomic disturbances may appear early in the disease, even prior to the motor symptoms, …
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Assessment of Proinflammatory Cytokines as Biomarkers for Parkinson’s Disease
… to discriminate PD from control samples. Impact on Diagnosis/Treatment of Parkinson’s disease: There is no simple, early diagnostic tool for PD, and the disease is diagnosed … our predictions and translate our new diagnostic approach into the clinical setting. …
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Assessing the Safety and Efficacy of a Novel Enzyme Inhibitor in Reducing Neuroinflammation and Enhancing Neuroprotection in Parkinson’s Disease
… in people with PD. This data will provide crucial insights into the molecule’s central nervous system distribution and … the safety and efficacy of EC5026 in 36 people with early to mid-stage PD in a Phase 1b clinical trial: 18 will … doses escalated over a 28-day treatment period. Impact on Diagnosis/Treatment of Parkinson’s Disease: There are …
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MJFF’s Innovative, New Funding Program Addresses the Entire Therapeutics Pipeline
August 13, 2012
… you know that the Michael J. Fox Foundation for Parkinson’s Research funds industry? The Michael J. Fox Foundation … for PD, and Clinical Intervention Awards (CIA) programs into a single, streamlined funding opportunity. The TPP … 2012 on Wednesday, September 19th in a panel entitled “Early Stage Collaborations: When Do They Work?” Click here …
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Here to Make Parkinson’s History: Our Story So Far and What's Ahead
November 9, 2020
… (PD). We’ve worked every day to accelerate the pace of research, solve field-wide problems and make a tangible … helped move Parkinson’s research forward and translated into real results for people living with PD. The number of therapies to treat the symptoms of PD has nearly doubled since 2014, including two news treatments for …