… from LRRK2 PD patients have damage to their mitochondrial DNA (mtDNA). This appears to a reproducible readout of LRRK2 … or white blood cells (lymphoblasts). We will also test whether drugs that inhibit LRRK2 can ‘fix’ the … for those individuals with LRRK2 mutations. Anticipated Outcome:           Successful completion of this project will …

… Your pit stops can support Parkinson’s disease research this month. If … to your purchase at checkout all through April. The company also supported the Foundation over the weekend at … donated $10 for each employee that finished the race. Altogether, their goal is to donate $300,000 to MJFF with money …

… published a review of drug development against this target. Alpha-synuclein clumps into, scientists believe, toxic aggregates that damage cells … are hitting the right types of alpha-synuclein to stop PD. How do we measure alpha-synuclein? An objective, biological …

… helps them manage their disease. Five individuals talk about their routines — and how staying active is improving their physical … hurt to keep it up. What Else Helps? I’ve been a part of a clinical study for the past five years. I’ve learned a …

… Linda and Joe Keilman on a recent trip to Colorado. “We have to do something,” says Linda Keilman about why she and her husband Joe are committed to participating in BioFIND —a clinical study … read about clinical research and spoke to her doctor about how she could participate. Joe learned that people without …

… with the disease. Neurons depend on energy provided by mitochondria, a subcellular structure that contains its own DNA. Defects in mitochondrial DNA can cause a failure in energy production, … Eduardo Tolosa Sarró, MD, PhD …