-
Mu Opioid Receptor Target for Levodopa-Induced Dyskinesia: Stop or Continue? (MOR4LID)
… Objective/Rationale: The mu opioid receptor (MOR) has long been proposed as an appealing target for managing levodopa-induced dyskinesia and therefore … test antagonists of the kappa and delta receptors to get a comprehensive analysis. The project therefore aims to …
-
5 Lessons I Learned about Parkinson's Disease Support Groups
January 23, 2015
… Rattle and Roll . It was a warm day in May 2005 in Sacramento, I felt as though I was the only person in the world … DBS. Tom and I each kept our worries about DBS to ourselves—how would I function after DBS; would I survive the surgery. … The group has provided education and support, and we have come to the conclusion that we are not alone in our quest …
-
Podcast: New to Parkinson’s? Steps to Take Today (Webinar Replay)
April 27, 2022
… MD, director of the American Parkinson Disease Advanced Center of Research; professor of neurology; principal … not yet taking PD medication. Connect with the PPMI team today at michaeljfox.org/podcast-ppmi-sites . Anyone over … . Christina Destro Associate Director Research Communications …
-
LRRK2 Kinase Activity and Mitochondrial DNA Damage in Parkinson's Disease
… LRRK2 is a protein regulated by kinases (protein regulators) and is also subject to autophosphorylation … with LRRK2-related PD have damage to their mitochondrial DNA (powerhouses of the cell; mtDNA). We will screen the … determine whether the kinase activity of LRRK2 is a good target for reversing mtDNA damage. In the absence of reliable …
-
Enlisting Fashion and Family to Find a Cure
April 9, 2013
… Fashion to Figure Co-founders Nicholas and Michael Kaplan (right), … for Michael Kaplan. His great-grandmother created the first commercially-made maternity dress and founded the plus-size … in New York, New Jersey and Maryland), shoppers can show their support by purchasing a Team Fox bracelet for $2, …
-
A Proactive Approach to Parkinson's
April 25, 2019
… his daughter. Charles Leblow, a 65-year-old resident of Clayton, California, doesn't do anything halfway. So in 2014, … Tea learned that he had Parkinson's disease, he got on his computer and started doing research. "One of the first … his symptoms and health helps him keep better track of how he is doing. "When the reminders come up on my computer, …