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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Integrated Analysis of Alpha-synuclein in the North American Prodromal Synucleinopathy (NAPS) Cohort

    Study Rationale: REM sleep behavior disorder is well recognized as a prodromal condition associated with a high risk of subsequently developing neurodegenerative disorders termed synucleinopathies...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Characterizing Molecular Subtypes in Parkinson’s Disease and Lewy Body Dementia

    Study Rationale: There is currently no disease-modifying treatment for Parkinson’s disease (PD) or Lewy body dementia (LBD). One possible reason is that both of these disorders are highly...

  • Research Grant, 2025
    Discovery of Alpha-synuclein PET Tracer for Parkinson’s Disease

    Study Rationale: In Parkinson’s disease (PD), a protein called alpha-synuclein builds up inside of brain cells. Research suggests that this protein accumulation damages the cells and eventually leads...

  • Research Grant, 2025
    Developing an ELISA Immunoassay for Monitoring Phosphorylation of Proteins Associated with Parkinson’s Disease

    Study Rationale: As Parkinson’s disease (PD) progresses, one of the molecular changes that occurs is an increase in the number of phosphate groups that are added to proteins. In this project, we will...

  • Research Grant, 2025
    Enhancing Recruitment of Individuals Traditionally Underrepresented in Parkinson’s Disease Research into the SPARX3 Clinical Trial

    Study Rationale: SPARX3 is a Phase 3 clinical trial designed to assess whether high intensity aerobic exercise can delay progression of Parkinson’s disease (PD) better than does moderate intensity...

  • Research Grant, 2025
    Construction of a Living Library of Digital Technologies for Use in Research and Care of Parkinson’s Disease.

    Study Rationale: Interest in digital technologies within Parkinson’s disease (sensors, devices, specific smartphone apps) for early detection and disease monitoring has increased in recent years. Over...

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