The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2021Hidden Sorrows of Covid-19: Impact of Stress on Parkinson’s Disease Progression
Study Rationale: People living with Parkinson’s disease (PD) are very sensitive to stress, which worsens motor symptoms (such as tremor) and leads to anxiety and depression. Studies in animals suggest...
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Therapeutic Pipeline Program, 2021Wireless “Nanoelectrodes” as a Minimally Invasive Alternative to Conventional Deep Brain Stimulation
Study Rationale: Deep Brain Stimulation (DBS) has been used to ease motor symptoms in people with Parkinson’s disease (PD). This approach requires a surgical procedure to implant electrodes into the...
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Expanding Biological Understanding of PD, 2021Dissecting the Role of GBA1 and LRRK2 in Regulating the Formation of Lewy Bodies
Study Rationale: A key hallmark of Parkinson’s disease (PD) is the accumulation of alpha-synuclein aggregates inside neurons. These aggregates are known as Lewy bodies (LBs). Although mutations in...
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Research Grant, 2021Development of Alpha-synuclein and Tau Imaging Agents
Study Rationale: Accumulation of alpha-synuclein and tau protein aggregates are pathological hallmarks of Parkinson’s disease (PD) and Frontal Temporal Dementia (FTD), respectively. The appearance of...
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Outcome Measures, 2021Protective Effect of Immune Gene Subtype in Parkinson’s Disease
Study Rationale: Our genetic studies of Parkinson’s disease (PD) have found a protective effect of an immune gene called HLA-DR, specifically the presence of the HLA-DRB1*04 subtype. We found that HLA...
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Research Grant, 2021Development of Selective PET Imaging Agents for Alpha-synuclein and Tau
Study Rationale: The ability to detect and monitor the accumulation of tau and alpha-synuclein aggregates in the brain is crucial to better understanding the pathophysiology of Progressive...
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Our funding programs support basic, translational and clinical research from academia and industry.