… The Michael J. Fox Foundation (MJFF) is presenting stories from the worldwide Parkinson’s disease (PD) community to share commentary, best practices, tips and … people living with Parkinson’s, but I have a few ideas on how we can spend time productively, or perhaps sometimes, …

… Constipation is a non-motor symptom of Parkinson’s disease that causes great discomfort and can decrease the body’s ability to absorb … assessment at five study visits. The investigators hope to show that RM-131 improves the symptoms of constipation in …

… positive results from its first-in-human LRRK2 inhibitor clinical trial. The experimental treatment is safe, and … can do). Denali also shared it is testing a second compound in a separate Phase I trial in control volunteers. … In a press release, the company announced its first trial showed greater than 90 percent inhibition of LRRK2 activity …

… Objective/Rationale :   Our objective is to demonstrate that an intervention program based on motor … Similar principles will apply for the CLG training; however, the RAS will be elicited automatically by a device … its amenability to appropriate therapy.    Anticipated Outcome :  We anticipate that after intensive training, the …

… Sharing Pioneer Award. Dr. Diane Stephenson, executive director of CPP, presented the award to the Foundation in recognition of our commitment to access and usability in research data. Dr. Stephenson specifically noted how we facilitated CPP’s access to data from interventional …

… urgently needed. We have developed a radioactively labeled compound, MODAG-005, that binds specifically to aggregated alpha-synuclein. This tracer should allow … In this study, we will confirm that MODAG-005 shows favorable properties in a model of PD. We will begin by …