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Michael J. Fox Talks Parkinson's Policy Priorities with POLITICO
March 6, 2017
… J. Fox sat down with POLITICO reporter Daniel Lippman to discuss the Foundation's policy priorities and why they … or other neurological conditions that are going to become more pressing as ever soon. I think of health first as … and has hopes and aspirations and maybe they align with where our ideal is, maybe they don't. But that process …
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Ask the MD: A Team Approach to Parkinson’s Fitness
September 6, 2019
… improves mobility and sleep, boosts mood and may contribute to positive brain changes that slow disease progression. … training in exercising programming for older adults or become certified to instruct a Parkinson’s-specific exercise … all the exercise in the world will not be enough. That's where exercise specialists come in. They can help people …
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MJFF Launches Funding Program to Promote Diversity, Equity and Inclusion in Parkinson’s Research
February 9, 2021
… of Parkinson’s disease (PD) is growing but remains far from complete. Unfortunately, most of this research has not been … socioeconomic, gender, sexuality and geographic spectrums. To address the knowledge gap, The Michael J. Fox Foundation … risk and developing treatments for all people. Please visit our Promoting Diversity, Equity and Inclusion in …
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Hit-to-Lead Optimization of Parkin Activators through Structure-Function Analyses
… Objective/Rationale: This project aims to develop potent small molecule activators of Parkin, which … Under normal conditions the Parkin enzyme is very compact and it needs to open up in order to become active. … Parkin’s compact structure in silico . With this we can predict molecules that bind to particular regions, lead to …
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Farnesoid X Receptor to Reduce Neuroinflammation
… Study Rationale: Although the precise mechanism(s) for neurodegeneration in Parkinson's … suggests that neuroinflammation is an important contributor. In this study, we will use pre-clinical models of PD to … models of PD that both have significant inflammatory components. Existing drugs/compounds that target the …