-
Get Moving! Work Out Your Parkinson’s Symptoms with Annette O'Brien
March 19, 2013
… their disease. In this ongoing series, individuals talk about their routines — and how staying active is improving … three-wheeler bike, Trixie. My husband, Neill, and I bike together, and often visit my grandkids. Even if I’m having … others who have PD. You may think you’re alone, but you come to realize how many are touched by it — and are working …
-
Team Fox Young Professionals of Washington DC to Host Golf Event
May 12, 2014
… of DC will co-host the 5th Annual St. John’s Cup Golf Tournament in partnership with St. John’s Lodge of the … Base at 2:30pm. Golfers of all levels are encouraged to come out and enjoy this unique golfing experience! Teams … will gather together at the St. John’s Cup Banquet where guests will dine, drink, mingle, and bid on exciting …
-
Gene Therapy Approach to Reduce Alpha‐synuclein Aggregation in a Model of Parkinson's
… protein alpha-synuclein inside brain cells. The team plans to use a gene therapy approach to insert a gene into a model … a viral vector gene therapy approach can be used to express a factor in brain cells that reduces abnormal … in the development of clinical grade viral vectors for testing in clinical trials. …
-
Development of a Protein Biomarker Panel to Measure Parkinson’s Disease Heterogeneity and Progression
… Study Rationale: According to The Michael J. Fox Foundation, the need for biomarkers … an objective assessment for Parkinson’s disease (PD) “has become more urgent as more projects enter human testing.” Such … and assessing drug efficacy. Octave has developed a precision-care platform for multiple sclerosis that includes …
-
Using Neurophysiology as a Stratification Tool for Synucleinopathy
… for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly, … stimulation (TMS) — to assess neurophysiological markers. Combining these techniques may help to reveal the … measurements to quantify cortical brain activity. The TMS test will be paired with nerve stimulation to measure …
-
Effect of LRRK2 Mutations on PD-associated Inflammation
… are also associated with PD, and recent evidence points to a role for LRRK2 to modulate inflammatory pathways. This … with LRRK2 mutations who have and who do not have PD. Outcomes will provide more information on the role of … This suggests that inflammation outside the brain may represent an early sign of Parkinson's disease; however, …