The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2009Testing PDE-1 Inhibitor in MPTP-treated Macaques
Promising Outcomes of Original Grant:
Our goal is to develop novel therapeutic molecules that promote normal dopamine neurotransmission in the brain affected by PD. We hypothesize that these molecules... -
MJFF Research Grant, 2009Investigating Placebo Effects in Parkinson's Disease with Functional MRI
Objective/Rationale:
Many researchers believe that placebo treatments may have beneficial effects on symptom progression in Parkinson’s disease, but there is very little experimental evidence on... -
MJFF Research Grant, 2009The Validation of Anxiety Scales in Parkinson's Disease
Objective/Rationale:
This study has two objectives:
1. To assess the occurrence and symptoms of anxiety disorders in Parkinson's disease, including atypical anxiety syndromes, and anxiety states... -
Novel Approaches to Drug Discovery for Parkinson's Disease, 2009Inhibition of Brain-Dependent Nitric Oxide (NO) Over-Production by Isoform-Selective NO Synthase (NOS) Inhibitors
Objective/Rationale:
The project objective is to test whether custom-designed, small-molecule, isoform-selective NOS inhibitors can reduce brain and systemic nitric oxide levels and show improved... -
Novel Approaches to Drug Discovery for Parkinson's Disease, 2009Development of HSF1 Effectors as Parkinson's Disease Therapeutics
Objective/Rationale:
This project will focus on the development of small molecule therapeutics to treat Parkinson’s disease by advancing lead compounds that modulate protein chaperones. Protein... -
Novel Approaches to Drug Discovery, 2009Optimizing Metalloporphryins for Clinical Development
Objective/Rationale:
Oxidative stress is a well-defined therapeutic target for Parkinson’s disease (PD) and antioxidant therapy is one of the most promising neuroprotective strategies for its...
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Our funding programs support basic, translational and clinical research from academia and industry.