The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP CRN Competitive Renewal Opportunity, 2025Examining the Dual Role of Neural Activity in Parkinson’s Disease
Study Rationale: Most previous work on brain circuitry in Parkinson’s disease (PD) has focused on what happens after the loss of dopamine neurons. However, we know that changes in the function of...
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iPSC Phenotyping Environmental Exposure Program, 2024Using Stem-cell Derived Brain-chip Technologies to Evaluate the Contributions of Environmental Toxins to Parkinson’s Disease
Study Rationale: Chronic exposure to environmental contaminants is believed to play an important role in the initiation of Parkinson’s disease (PD). With an estimated 40,000 to 60,000 chemicals that...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025Investigating the Mechanisms of Alpha-synuclein-induced Anxiety in a Novel Preclinical Model of Parkinson’s Disease
Study Rationale: Although Parkinson’s disease (PD) is known as a movement disorder, non-motor symptoms like anxiety can severely reduce individuals’ quality of life. Unfortunately, we know very little...
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Neuronal Synuclein Disease Endotypes 2024, 2025Identifying Biomarkers for the Common Mechanism Underlying the Disease Continuum from Parkinson’s Disease to Alzheimer’s Disease
Study Rationale: Disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) share many similarities in their pathology. In particular, both involve accumulation of amyloid-β and alpha...
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Measuring Alpha-Synuclein in Extracellular Vesicles, 2025Measurement of Alpha-synuclein in Plasma Extracellular Vesicles after Automated Isolation
Study Rationale: Extracellular vesicles are small, membrane-enclosed packages that all cells release into the blood. Because the contents of these packages reflect that of the cells from which they...
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iPSC Phenotyping Environmental Exposure Program, 2024Use of a Stem-cell-based Platform to Screen for Environmental Factors in Parkinson’s Disease
Study Rationale: Both environmental and genetic factors are believed to be involved in Parkinson’s disease (PD). Although the genetic mutations linked to PD have been studied intensively, it is...
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Our funding programs support basic, translational and clinical research from academia and industry.