The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Improving Levodopa Delivery, 2011Continuous Subcutaneous Levodopa Prodrug Infusion
Objective/Rationale:
Numerous studies demonstrate that continuous levodopa infusion can result in reductions of more than 50 percent in time spent in the "off" state and time spent with severe... -
Target Validation, 2011Caspase-8 Control Microglia Activation and Neurotoxicity in Parkinson's Disease
Objective/Rationale:
Sustained microglia activation and resulting neuroinflammation is believed to play an important role in the mechanism of chronic dopaminergic neuronal loss in Parkinson’s disease... -
MJFF Research Grant, 2011Development of Highly Sensitive and Specific Antibodies Against Oxidized DJ-1 as a Biomarker for Parkinson's Disease
Objective/Rationale:
Mutations in the DJ-1 gene are associated with an early-onset familial form of PD and DJ-1 protein has been shown to be lower in the CSF of sporadic PD compared to controls. DJ-1... -
Defining Cognitive Phenotypes of Parkinson’s Disease, 2011Neurochemical Correlates of Cognitive Phenotypes in PD
Objective/Rationale:
Parkinson’s disease causes neurodegeneration in multiple subcortical nuclei, including substantia nigra, locus coeruleus, dorsal raphe nucleus, and nucleus basalis. Each of these... -
LRRK2 Cohort Consortium, 2011Autonomic Profiles of LRRK2 Mutation Carriers with Parkinson’s Disease and Non-manifesting, First-degree Relatives
Objective/Rationale:
Autonomic disturbances are common symptoms of Parkinson’s disease (PD). We propose to analyze data on autonomic function collected from PD patients and relatives of PD patients... -
Research Grant, 2011Pre-clinical Development of Encapsulated Cell Biodelivery of GDNF for Parkinson's Disease
Objective/Rationale:
Glial cell line-derived neurotrophic factor (GDNF) is a protein that can aid in survival of the dopamine cells that die in Parkinson’s disease (PD). Treatment with GDNF in PD has...
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Our funding programs support basic, translational and clinical research from academia and industry.