The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Cell Line, 2002Generation of Transplantable Dopamine Neurons from Human Emryonic Stem Cells
The focal nature of neuronal loss suggests that cell replacement therapy may be suitable for Parkinson's disease. Indeed, transplanted fetal midbrain cells survive in some Parkinson's patients for...
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MJFF Research Grant, 2009Clinicogenetic Studies of LRRK2 G2019S in Tunisia
Objective/Rationale:
Parkinson’s disease (PD) is a prevalent, heterogeneous disorder with a complex, multifactorial etiology. In Tunisia, North Africa, the burden of genetically-defined LRRK2 G2019S... -
MJFF Research Grant, 2009Biomarker Battery Assessment in LRRK2
Objective/Rationale:
Parkinson disease (PD) has a pre-clinical phase characterized by death of dopamine neurons in the substantia nigra and other brain regions, which precedes the development of... -
MJFF Research Grant, 2009DAT Imaging in Ashkenazi Jews (AJ) LRRK2 Gene Carriers - a consortium proposal
Objective/Rationale:
While most PD is not associated with a specific genetic cause, in some ethnic populations such as Ashkenazi Jews there is a high prevalence of a genetic cause for PD affecting a... -
Rapid Response Innovation Awards, 2009Accurate Drosophila Genetic Models of LRRK2-based Parkinson's Disease
Objective/Rationale:
The most common hereditary form of Parkinson’s Disease (PD) results from mutations of the LRRK2 gene in humans. The model genetic organism, Drosophila melanogaster (fruit fly)... -
Rapid Response Innovation Awards, 2009Uncovering Factors that Prevent Dopaminergic Neuronal Degeneration in a Novel C. elegans Model for Parkinson's Disease using a High-throughput Forward Genetics Approach
Objective/Rationale:
Our inability to slow down the progression of Parkinson’s disease (PD) reflects our incomplete knowledge of the molecular mechanisms that cause the selective death of dopaminergic...
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