To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
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RILPL2 Antibody (Ms)
Antibody
Rabbit monoclonal antibody directed against mouse RILPL2 for immunoblotting, immunostaining, and immunoprecipitation applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
Rab 12 pS106 Phosphospecific Antibody (WB/PRM-MS)
Antibody
Rabbit monoclonal antibody directed against human Rab12 when phosphorylated at Serine106 (pS106 Rab12). Developed for use in immunoblot and PRM-MS applications.
SNCA Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in SNCA, including- -A30P (heterozygous and homozygous)
- -A53T (heterozygous and homozygous)
- -E46K (heterozygous and homozygous)
- -DOX-NGN2 + TMEM192-HA + A53T (heterozygous and homozygous) - in development, est late 2026
SNCA A53T Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with SNCA A53T mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
SNCA A30P Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with SNCA A30P mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
LRRK2 G2019S Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with LRRK2 G2019S mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
DJ-1 Exon 1-5 Deletion Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with DJ-1 Exon 1-5 deletion. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
GBA IVS2+1 Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with GBA IVS2+1 mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
Parkin Exon 3 Deletion Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with PRKN Exon 3 deletion. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
PINK1 Q129X Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with PINK1 Q129X mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic