Dr. Reynolds was trained in pharmacology at the University of Leeds (UK), the Johns Hopkins University School of Medicine, and the University of Chicago, where he received a BSc, PhD and post-doctoral training, respectively. He has been in the Department of Pharmacology at the University of Pittsburgh since 1988, where he is currently professor and vice-chair, and where he is also the director of the PhD program in Molecular Pharmacology. Dr. Reynolds' laboratory has focused on the study of ion-induced injury of neurons for a number of years, and these studies have investigated the role of calcium, magnesium and zinc in neurodegeneration. Over the past several years the lab has developed interests in the role of mitochondria in neuronal injury, and is currently investigating the life history of mitochondria in central neurons. Dr. Reynolds serves on the editorial board of several journals, including the Journal of Neuroscience, Molecular Pharmacology and Mitochondrion, and he was just appointed as a Deputy Chief Editor of the Journal of Neurochemistry. He also serves as a regular member of the Neurodegeneration and the Biology of Glia study section at NIH.