Leon Murphy, PhD, is an industry-leading expert in Autophagy, mTOR and PI3-Kinases and has broad expertise building and leading teams that develop novel therapeutics for cancer, neurodegeneration and metabolic disorders. With experience in large Pharma and early-stage biotechnology companies Leon has over 20 years of drug discovery and development experience. He is currently the Chief Scientific Officer at Casma Therapeutics, a Massachusetts-based biotechnology company focused on the Autophagy-Lysosomal system. Prior to joining Casma Leon was an entrepreneur-in-residence at Third Rock Ventures (Boston MA) where he helped develop the scientific and business strategy for Casma Therapeutics. He is recognized as a leader in the autophagy-lysosomal field and has published multiple papers in high-impact journals. Leon’s formal training was in biochemistry and cell biology.
Associated Grants
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Development of in Vivo Biomarkers for TRPML1 Target Engagement and Analysis of Therapeutics
2025