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Physiological Role of Lysosomal LRRK2 in the Regulation of CMA
… Brain cells rely on very efficient surveillance systems to identify defective components and break them … Project Description: These researchers have developed systems that permit them to reconstitute each of the steps … to their delivery and destruction in the cellular cleaning systems. Using these methods, they intend to add normal …
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LRRK2 Safety Initiative
… LRRK2 kinase inhibitors in the clinic. If we confirm that multiple LRRK2 kinase inhibitors are a safety liability, we …
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Identification of binding proteins for alpha-synuclein oligomers in brain and cells
… therapies. Final Outcome Dr. Jensen successfully identified multiple oligomer-specific targets. He is now conducting a …
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Rita Balice-Gordon, PhD
… and gene therapy for patients with rare genetic disorders, multiple sclerosis and neurodegenerative diseases. She …
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PDKit: A data science toolkit for the digital assessment of Parkinson's Disease
March 12, 2021
… methods that allow the comparison of results across multiple centres and hardware variations. PDkit adopts the …
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Rita Balice-Gordon, PhD
… and gene therapy for patients with rare genetic disorders, multiple sclerosis and neurodegenerative diseases. She …