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The New York Times: Seeking a Shorter Path to New Drugs
November 15, 2009
… foster faster innovation. It’s a holistic approach, called “systems thinking,” that originated in methods that engineers … of the practice of aeronautics and astronautics, and systems engineering, at M.I.T. Aeronautics had to re-examine … she calls it — that would force them to make large-scale, systemic changes. Perhaps that’s why initiatives at M.I.T. …
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The Michael J. Fox Foundation for Parkinson's Research Awards $3 Million To Develop New Technologies for Gait & Balance Issues in Parkinson's
February 4, 2019
… Belgium and mHealth Technologies are developing the DeFOG system , which is a smartphone-based wearable system that delivers personalized cueing (a type of prompt) … Institute of Chicago is testing a smart, wearable airbag system to prevent injury in Parkinson's patients at risk of …
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Clinical Assessment of Patients with PD Who Underwent DAT Scan and FDG PET at the Early Stages of Their Extra-Pyramidal Disorder as Part of Their Initial Workup
… between these mutations and the pre-synaptic dopaminergic system or the brain metabolic activity. We aim to … brain metabolism and the pre-synaptic dopaminergic system while exploring the added value of FDG PET in the … the LRRK2 and GBA genes and the pre-synaptic dopaminergic system and whole brain metabolic activity mainly because …
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Distribution of a Dominant-negative Inhibitor of Tumor Necrosis Factor
… blood-brain barrier (BBB) allows only a small fraction of systemically administered small-molecule drugs and even … developed for disorders of the central nervous system (CNS) to reach therapeutic concentrations in the … we will employ the SynchroMed II® implantable infusion system and manipulate a variety of infusion parameters to …
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Study: Novel Therapy Limits ‘Wearing Off’ Periods Associated with Parkinson’s Drugs
December 11, 2012
… to treat Parkinson’s that don’t focus on the dopamine system. Other so-called “non-dopaminergic” drug candidates … from Addex Therapeutics, targets the brain’s glutamate system to limit dyskinesia in people with PD. Pimavanserin … from Acadia Pharmaceuticals, targets the brain’s serotonin system in treating the psychosis that is sometimes a side …
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Funding for Neurological Disease Database Passes the Senate
August 30, 2018
… for the National Neurological Conditions Surveillance System. This database will capture demographic information … Once the National Neurological Conditions Surveillance System is fully funded, it will be a valuable resource for … diseases the National Neurological Conditions Surveillance System will track, The Michael J. Fox Foundation is working …