… PD-affected and healthy individuals collected from multiple international sites. These samples were genotyped … it is possible that more complex interactions involving multiple SNPs (perhaps in combination with environmental …

… Brain cells depend on very efficient surveillance systems to identify defective components and break them … to develop drugs to enhance the activity of this cleaning system as a possible future treatment for PD. This is an … obtained very promising results in cellular experimental system that have encouraged us to consider further …

… Ulm University in Germany — outlined a Parkinson’s staging system, which describes the regional distribution and … process of Parkinson’s may begin in the peripheral nervous system before migrating to the brain. “Professor Braak’s … that alpha-synuclein aggregation could begin in the nervous system of the gastrointestinal tract and migrate from there …

… a laboratory devoted to the study of enteric nervous system and enteric neuropathies. …

… Cao Xiao is a PhD candidate in industrial and systems engineering at University of Washington, Seattle. …

… to the accumulation of the toxic protein alpha-synuclein. Systems within neurons able to clear alpha-synuclein become … developing therapies aimed at improving the ability of such systems to reduce alpha-synuclein. Trehalose is a safely …