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Senate Votes Against Health Care Reform
July 28, 2017
… rejected a bill to reform our health care and insurance systems. This was the last of three proposals the Senate … members on both sides of the aisle to create a health care system that meets the needs of people with Parkinson's and …
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Pekka Kallunki, PhD
… pharmaceutical company solely devoted to central nervous system (brain and spinal cord) disorders. …
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The Nur77/RXR Transcriptional Complex as a New Target in L-Dopa-induced Dyskinesia Treatment
… movements. The general objective of the proposal is to demonstrate that Nur77 and RXR can be targeted to reduce … both heterodimer partners (Nur77/RXR as a transcriptional complex) are necessary, we will investigate the effect of … models (gene rescue), using a virally driven gene delivery system, exacerbated dyskinesia. This transcription …
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Nmnat Function in Axonal Neuroprotection
… Nmnat1 Gene Therapy for Parkinson's Disease Promising Outcomes of Original Grant: In the previous application, we tested the hypothesis that gene delivery of NMNAT-1 would protect striatal innervation in … Neurodegeneration … Academia/Nonprofit …
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The Impact of Oligomerization on Alpha-Synuclein Toxicity
… will test the toxicity of these mutants in an experimental system by investigating dopaminergic loss in the substantia … The dual approach (in vitro characterization in a cell free system and the in vivo approach) will allow us to correlate … we tested the toxicity of these mutants in an experimental system by investigating dopaminergic loss in the substantia …
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Wearable Sensors and a Web-Based Application to Monitor Patients with Parkinson's Disease in the Home Environment
… Project Description: The study aims to develop a Web-based system to monitor subjects in their homes with miniature … measure the severity of Parkinson’s symptoms. The Web-based system will provide videoconferencing capability, access to … Outcome: The project will provide the first Web-based system to remotely access sensor data recorded from …