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Daiani Machado de Vargas
… As a doctoral student at the same institution, she used systems biology bioinformatics tools to establish signature …
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Cynthia A. Kelm-Nelson, PhD
… both health and Parkinson disease. Her work utilizes a true systems biology approach, encompassing behavioral, genomic …
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Graeme Mardon, PhD
… and has proven to be an excellent in vivo animal model system for developmental and degenerative processes directly … Parkinson's disease that cannot be matched by any mammalian system. As new genes are identified and characterized, we … using both Drosophila and the mouse as animal model systems. While at Baylor, Dr. Mardon has published a series …
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Development of LRRK2 Target Engagement Ligands
… While PET tracers have been developed for the dopaminergic system, a key neurotransmitter system affected by PD, there are no currently available …
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Pharmacological Targeting of Inflammasome Activation Mechanisms in Synuclein Models of Parkinson's Disease
… Our previous studies confirmed the activation of an immune system complex called the inflammasome is involved in … progression by blocking persistent activation of the immune system and chronic brain inflammation. Importance of This …
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Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s Disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity
July 6, 2020
… disease (PD) is a disease of the central nervous system that progressively affects the motor system. Epidemiological studies have provided evidence that …