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Responsive, Closed-Loop Approach to Treat Freezing of Gait in Parkinson’s Disease
… that may lead to freezing of gait in order to develop a DBS system to target this symptom. Hypothesis: We posit that we can develop a “smart” DBS system that will monitor the GPi and the PPN (and the …
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Functional Evaluation of Alpha-synuclein Dosage Effects in CRISPR‐edited SNCA Model
… cell lines to address variability of the cell model system, to characterize potential off-target effects of … or related alpha-synucleinopathies. Our unique cell model system of different alpha-synuclein gene copies at the …
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Tagging Genes Associated with Parkinson’s Disease Using the Gene-editing CRISPR Tool
… cells affected in the disorder. We will use a gene-editing system to fuse a small, light-emitting tag to candidate PD … cells. Finally, using a microscope and a highly sensitive system for detecting the tags, we will find out where these …
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Filling in Gaps: MJFF Offers Funding to Extend California Parkinson’s Registry
November 12, 2020
… to conduct this program and model to guide data collection systems in other states. The U.S. Centers for Disease … launched the National Neurological Conditions Surveillance System to begin to piece together various national and state …
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Non-profits in Neurodegenerative Space Publish Paper on Working Across Diseases
August 7, 2024
… centers around the development of a biological staging system for “Neuronal alpha-Synuclein Disease” (NSD) , which … and additional non-profits to discuss the staging system for research, leading to important input from …
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Flurry of Investor Activity Accelerates Parkinson's Therapies through Development
September 24, 2014
… million Company: Neuroderm Project: ND-0612 is a pump-patch system of delivering levodopa and carbidopa continuously, … Investment: $2.5 million Company: Sapiens Project: Their system optimizes localization of deep brain stimulation to …