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Yahoo! Sports: Disease Can’t Slow Roach’s Ascent
November 12, 2009
… him alive and well. There’s no greater therapy, physical or mental, than round after round in the ring, “40 or 50 a …
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Wired Magazine: Sergey Brin's Search for a Parkinson's Cure
June 23, 2010
… and acrobatics, is drawn to: equal parts physical and mental exertion. “The dive itself is brief but intense,” he … adjust his algorithm by counteracting his DNA with environmental factors. “This is all off the cuff,” he says, “but … still didn’t connect his mother’s Parkinson’s to his own health. Then, in 2006, his wife-to-be, Anne Wojcicki, …
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Targets to Therapies Initiative
… These efforts will address critical gaps, define experimental approaches, and evaluate the feasibility and impact … Consulting Limited Amanda C. Mitchell, PhD Valo Health Andy Singleton, PhD Global Parkinson’s Genetics … PhD Abbvie, Neuroscience Discovery Jessica Sadick, PhD Valo Health Jonas Hannestad, MD Independent Jonathan Behr, PhD …
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Describing the Structure and Function of LRRK2
… better understand how this important protein functions in healthy and PD-affected brain cells, we will study the … LRRK2 structures will help us understand its function in health and disease. Also, we hypothesize that microtubules — …
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Validation of USP30 as a Therapeutic Target for Parkinson's Disease Modification
… mitochondria to see if mitochondrial function and neuron health is improved. We will also develop profiles of USP30 …
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Parkin-activating Small Molecules in a Model of Mitophagy
… Rationale: The protein parkin plays a critical role in the health and maintenance of the brain cells that make …