… These methods have been successfully applied to diverse systems such as viral glycoproteins, membrane protein …

… Ph.D. studies, Dr. Moraud pioneered the first closed-loop system to control spinal-cord neuromodulation for the …

… inhibit LRRK2 in peripheral tissues when the mice are dosed systemically. A pre-clinical model treated with LRRK2 ASOs, either locally in CNS or systemically, does not present signs of toxicity (up to 8 …

… the control of a separate, relatively autonomous, nervous system located in the stomach and intestines called the “enteric nervous system”, or ENS, that contains nearly as many nerve cells as …

… levodopa. Our recent studies have identified the serotonin system as a possible target for antidyskinetic therapy. … patients.  Final Outcome In recent years, the serotonin system has emerged as a key player in dyskinesia. Here we …

… The neural network of the gut called the enteric nervous system (ENS) is affected by the pathological process in PD. … considered the digestive counterpart of the central nervous system blood-brain-barrier), which is regulated by the EGC. …