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Parkinson’s Disease Vaccine Treatment Approach Awarded $8M
April 29, 2014
… developing vaccines against Parkinson’s disease (PD) and multiple system atrophy (MSA). The Michael J. Fox Foundation granted AFFiRiS …
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SUPPLEMENT: Rescreening of the MJFF Compound Library to Identify Molecules that Can be Used to Monitor Alpha-synuclein
… sections taken from the brains of people with PD and with multiple system atrophy (MSA) using the tritium-labeled versions of BF3620 …
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PET Tracer to Support Trials of Drugs Inhibiting Neuroinflammation via the NLRP3 Inflammasome
… diseases such as Alzheimer’s, motor neuron disease, and multiple system atrophy. Next Steps for Development: Once the PET tracer has …
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Is Parkinson’s Disease a Low-grade Inflammatory Bowel Disease?
… in the ascending colon, 2 in the descending colon) have already been performed in 19 PD patients, 14 control subjects … system atrophy. Each PD patient had a neurological (disease duration, UPDRS III score, cumulative dose of … role of intestinal inflammation in PD. Anticipated Outcome: We anticipate that the present study will demonstrate …
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Using the Chemical Modification of Alpha-synuclein to Define Disease State and Facilitate Patient Stratification in Parkinson’s Disease
… to discriminate between PD, Dementia with Lewy body (DLB), Multiple system atrophy (MSA) and healthy controls, which will allow us to …
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Maximizing the Sensitivity of Seed Amplification Assays Used to Detect Alpha-synuclein Aggregates
… but distinguishable protein aggregates involved in PD and multiple systems atrophy (MSA). Impact on Diagnosis/Treatment of Parkinson’s …