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Autophagy and Mitochondrial Dysfunction as Potential Therapeutic Targets in Inherited Parkinson's Disease
… mitochondrial function and, therefore, improve cells' health. We also aim to determine whether autophagy …
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Studying the Impact of Alpha-synuclein on Fatty Substances to Identify New Parkinson's Disease Drug Targets
… interactions of alpha-synuclein and lipids are important in health and disease, there are currently no therapeutics …
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QE3 Trial Ancillary Biomarkers Study
… about a disease like PD, such as whether or not an experimental treatment like coenzyme Q10 is actually changing the … in the brain and whether or not it is truly influencing the health of brain cells. Project Description: A random sample … of the trial and later after they have been on the experimental treatment for six months. The samples will be …
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Biomarkers in Human Cerebrospinal Fluid
… funding was received from the National Institutes of Health through its R01, P42, R21 and P01 grant mechanisms. …
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The Influence of Bacterial Amyloid on Alpha-synuclein Misfolding in a Pre-clinical Model
… of the bacteria residing in our intestines for human health and disease. The results will be valuable for …
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The Michael J. Fox Foundation Calls for Collaboration in Genetic Studies
October 2, 2003
… data to derive more significant conclusions about a fundamental question in Parkinson’s disease. They will be … genetic database administered by the National Institute of Health (NIH). Letters of intent are due by November 12, …