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(SUPPLEMENT) The Foundational Data Initiative
… grant builds upon the research from a prior grant: Using a Systems-based Approach to Study the Molecular Processes … therapeutic intervention. Hypothesis: We hypothesize that systems-based approaches, combined with complex genetics, … of novel therapeutics against identified targets. This system can also be used to test whether an intervention …
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Examining the Dual Role of Neural Activity in Parkinson’s Disease
… earliest events leading to PD in genetically defined model systems and elucidating the mechanisms involved, we will …
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Characterization of a Preclinical Model Bearing a Parkinson’s Disease–linked Mutation in PLA2G6
… the mutation leads to disturbed movement and nervous system pathology similar to that seen in people with PD. We …
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Validation of Functional Staging of Parkinson’s Disease Using the Critical Path for Parkinson’s (CPP) Integrated Parkinson’s Database
… alpha-synuclein in spinal fluid and adopting a staging system based on measures (or scales) of cognitive and …
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Development of Brain-penetrant TrkB Agonist Antibody for Parkinson’s Disease
… barrier, we have coupled it with a "brain shuttle" system that ferries it into the brain. In this study, we …
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Ask the MD: Walking, Balance and Parkinson's
January 25, 2018
… and even technological treatments, such as virtual reality systems. Watch the video to learn more. Watch a webinar or …