Your search for “Multiple System Atrophy” returned 2622 results.
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Delivery of Kinase-Modified LRRK2 to Dopaminergic Neurons Using High-Capacity Viral Vectors
… year one, we created a panel of high-capacity viral vector systems to deliver full-length wild type and kinase modified …
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Development of G2019S Selective LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
… molecular targets must be examined in experimental model systems. LRRK2 is a protein kinase that appears to be a key …
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5-alpha-reductase Inhibition for the Treatment of Levodopa-induced Dyskinesia
… neuronal activities) in the modulation of the dopaminergic system. We recently demonstrated that 5-alpha reductase …
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Activation of Microglial LRRK2 by Alpha-synuclein: LRRK2 Pathogenesis in Idiopathic PD
… inflammation will be examined in microglial cell culture systems and in pre-clinical models that use alpha-synuclein …
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Investigation of LRRK2 as a Regulator of Microglial Cell Function
… known as microglia, the main immune cell of the nervous system. Researchers hypothesize that PD-associated LRRK2 …
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α-Synuclein in Plasma-Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease
May 18, 2021
… in extracellular vesicles derived from the central nervous system and may contribute to the spreading of disease …