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Civitas Therapeutics Announces MJFF Grant to Study Lead Drug Candidate for Parkinson's Disease
November 29, 2011
… CVT-301’s ability to deliver more rapid and consistent systemic exposure of L-dopa compared to oral administration. … Disorders Center, University of Pennsylvania Health System, and a member of the Civitas Scientific Advisory … programs encompass respiratory disease, central nervous system disorders, and infectious disease. Civitas …
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Parkinson's Disease Genetics Sequencing Consortium
… This project will help identify novel biological systems to develop a knowledge base working toward a pathway …
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Role of GTPase Activity in Neurodegenerative Phenotypes Induced by G2019S LRRK2 in a Pre-clinical Model of Parkinson’s Disease
… different forms of human LRRK2 in the nigrostriatal (brain system) dopaminergic pathway and will introduce synthetic …
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Validation of Uncharacterized LRRK2 Phosphorylation Sites
… kinase. Study Design: We will generate antibodies (immune system proteins) that recognize LRRK2 when phosphorylated at …
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Novel Nicotinic Receptor Agonist for Treating Levodopa-induced Dyskinesia
… messenger) receptor subtypes are involved in nervous system responses to levodopa and, second, that activation of …
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K-ATP Channels and Their Role in the Survival of Nigral Dopaminergic Neurons
… that the channel is activated in neurotoxin based model systems for the disease and a deactivation has a protective …