Your search for “Multiple System Atrophy” returned 2622 results.
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Convection Enhanced Delivery to Study the Pathophysiology Underlying the Clinical Features of Human Parkinson's disease
… distribute a small molecule within discrete central nervous system nuclei in humans. 2. Determine the feasibility of …
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In Vivo Validation of the AAV-alpha-synuclein Vectors Generated by UNC for Distribution to MJFF Supported Research Community
… do not induce much pathology in the nigrostriatal system. On the other hand, viral vector mediated …
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Role of PINK1 and Parkin in Innate Immunity: Crosstalk between Mitochondrial Dysfunction and NLRP3 Inflammasome Signaling
… (PD). Overactivation of the inflammasome (innate immune system receptor) signaling complex NLRP3 is suspected to …
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Restoring the Nigrostriatal Pathway with Living Micro-Tissue Engineered Axonal Tracts
… targeted axonal outgrowth is limited in the central nervous system, our approach is it to a use tissue engineering …
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Enhancing Mitochondria Quality Control in Parkinson’s via Activation of the Caseinolytic Peptidase
… of the CLPP enzyme rescued PD-like health problems in model systems . Natural antibiotics that activate CLPP have …
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Comparison of Nedd4 and GBA for Improving Protein Handling and Reducing Alpha-synucleinopathy
… including alpha-synuclein. Lysosomal protein degradation systems fail in Parkinson’s disease (PD). Nedd4 and …