Your search for “Multiple System Atrophy” returned 2623 results.
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Effect of novel sirtuin inhibitors on alpha-synuclein toxicity in a Parkinson disease pre-clinical model
… treating PD and related disorders. Testing in a mammalian system is a crucial step toward establishing whether SIRT2 …
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Investigating Signaling Pathway Dysfunction Linked to LRRK2
… whether LRRK2 had an impact on a particular signaling system in the cell called the mTOR pathway. This pathway …
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Highly Selective M1 Muscarinic Receptor Positive Allosteric Modulators for the Treatment of Parkinson's Dementia
… activity in cholinergic brain circuits (chemical messenger system) to a limited degree. However, these drugs have …
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Inhibition of Brain-Dependent Nitric Oxide (NO) Over-Production by Isoform-Selective NO Synthase (NOS) Inhibitors
… isoform-selective NOS inhibitors can reduce brain and systemic nitric oxide levels and show improved …
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Study to Evaluate RM-131 Administered to Parkinson’s Patients with Chronic Constipation
… can be hard to treat. Constipation can happen when the GI system slows down, which can cause significant discomfort …
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Evaluation of the Microtubule-Stabilizing Agent, Epothilone D, in Mouse Models of Parkinson's Disease
… of the cells. Evidence from Parkinson’s disease (PD) model systems suggests that nerve cell function may be compromised …