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Thomas S. Scanlan, PhD
… at developing agents that penetrate the central nervous system for neurodegenerative diseases including multiple sclerosis, Alzheimer’s, and Parkinson’s disease. …
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Ganesh Iyer, PhD
… into life-changing treatments. Dr. Iyer has advanced multiple targets from assay development through … for assays supporting targets in the central nervous system and cancer. He holds a PhD in biochemistry from …
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Sjors Hendrik Willem Scheres, PhD
… of tau, α-synuclein, amyloid-b and TMEM-106B filaments from multiple diseases, revealing that specific folds … Recently, they have started the exploration of model systems that replicate the disease-specific structures. …
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Gut-to-brain Circuit Contributions to Parkinson-like Phenotypes in Disease Models
… the connections between neurons in the enteric nervous system, which regulates the gastrointestinal tract. This … anatomic and functional maps of macaque enteric nervous system (ENS) and central nervous system (CNS) PD-relevant … Parkinson’s Disease: Using powerful new technologies across multiple PD-relevant model systems, this project could …
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Stephen Gomperts, MD, PhD
… of amyloid, tau, dopamine cell loss and regional atrophy to cognition and disease course in PD and DLB, and …
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Richard Killick, PhD
… of a drug that inhibits synapse and neuronal loss, brain atrophy, cognitive impairment and the hallmark brain …