-
Studying Abnormalities of Immune System Aging in Parkinson's Disease
… promoting inflammation in the brain. As we age, the immune system becomes more "experienced," that is, effective in … able to respond to new infections. This aging of the immune system may play a role in PD. We have found evidence … protect against PD by limiting the ability of the immune system to become activated and cause brain inflammation. …
-
-
Characterization of Parkinson’s Disease Clinical Subtypes Using Multiple Immunologic and Genetic Markers
… We hypothesize that genetic data related to the immune system holds valuable information regarding the onset and … based on the available genetic data, focusing on the immune system. From these characterizations, we will extract …
-
Parallel Reaction Monitoring within the Parkin Ubiquitin Ligase System
… of more than a dozen mitochondrial proteins. Using this system, we closely followed the ubiquitylation process and …
-
Does Sporadic Parkinson's Disease Begin in the Enteric Nervous System?
… involves a few nerve cell types within the human nervous system. A retrospective cross-sectional post-mortem staging … Parkinson's disease begins outside of the central nervous system. Our project aims to test whether the enteric nervous system is hit first in sporadic PD. Project Description: …
-
June Third Thursdays Webinar Immune's System Role in Parkinson's Transcript
… June 2019_Immune System Webinar July 2018 Podcast_transcript.pdf …