… addresses this need by developing a unique human cellular system for the early identification and study of … investigator plans to grow skin fibroblasts derived from multiple Parkinson's patients and age-matched controls and …

… microglial activation. Particulary, there is evidence that systemic infections exacerbate disease progression in Multiple sclerosis, AD and prion disease models. We …

… Study Rationale: This study aims to compare the immune system of Parkinson's disease (PD) patients and their … clinical research efforts have implicated the immune system as a potential source of PD biomarker information. … the same environment. These samples will be evaluated for multiple inflammatory and immunological endpoints. We will …

… in Parkinson’s disease. Inflammation is an immune system response to injury or disease, but chronic … research. This initiative seeks to approach the issue from multiple angles, including:  Evaluating the prevalence of … that enhance survival of cell grafts in the nigrostriatal system; and Exploring immune status as a biomarker of …

… deposits around nerve cells in the brain leading to cell atrophy and death. Dr. Sierks is developing multifunctional …

… pathological markers of PD in both the peripheral nervous system and the central nervous system. These studies could lead to an earlier diagnosis of … Disease Consortium is a consortium of investigators at multiple institutions throughout Arizona: Mayo Clinic …