-
Phenoprofiling PD
… may also suffer so-called “non-motor features,” including problems with mental functioning, depression, falling asleep or staying awake, and autonomic functions (for example bladder and bowel problems). Furthermore, when patients are treated over the …
-
Understand Me for Life: An Intelligibility App for Parkinson's Disease
… 90% of people with Parkinson’s develop speech and language problems over the course of the disease, and more than half of these speakers experience problems with intelligibility (their ability to be … Me for Life app will be designed to target intelligibility problems in Parkinson’s disease. A total of 10 speakers will …
-
Untangling PINK1–Tau Crosstalk and Co-Morbidity Mechanisms in Parkinson’s Disease
… is a brain disorder that gets worse over time, causing problems with movement and cognitive abilities. Two key problems are often seen together in this disease: damage to … mice and human brain cell models will be used to test how problems with PINK1 lead to harmful changes in tau and how …
-
Glossary of Terms
… tolcapone. Tolcapone has been known to cause serious liver problems and has been withdrawn from the Canadian and … dysfunction , postural instability and gait dysfunction , sleep disorders , speech disorders , depression , and … other than movement. These include cognitive impairment, sleep problems and depression. These typically do not …
-
Jessika Suescun, MD
… clinical trials focusing on parkinsonism and REM sleep behavioral disorder as a prodromal condition. Her …
-
Ziv Gan-Or, MD, PhD
… who studies the genetics of Parkinson’s disease, REM sleep behavior disorder and other neurodegenerative …