… Disease:                      TGFB has been shown to have multiple associations with PD, as well as with the nigrostriatal system (a major dopamine pathway). However, no direct causal …

… Study Rationale: There is clear evidence that the immune system plays an important role in the development and … pathologic inflammation, to assess the potential effects on multiple symptoms associated with Parkinson's disease. Pre - …

… Multiple mutations have been described in the human GBA1 … and inflammation were not observed in the nigrostriatal system of this model. In summary, the GBA1 D409V KI mouse …

… based exercise strategies have potential to improve multiple physiological systems which determine disability in other condtions, …

… may be best understood through the contribution of multiple genes to multiple disease-relevant processes. Thus, Dr. Webber does … and models of gene functional relationships that allow multiple pathways and processes to intersect. His gene …

… Parkinson’s Research (MJFF) has launched the observational Systemic Synuclein Sampling Study (S4) to investigate the … research at the Institute for Neurodegenerative Disorders. “Multiple studies have demonstrated the significance of … biomarker, but none have measured alpha-synuclein levels in multiple biofluids and peripheral tissues in a single …