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Studies on the effects of peripheral inflammation on the progression of Parkinson ´s disease
… microglial activation. Particulary, there is evidence that systemic infections exacerbate disease progression in Multiple sclerosis, AD and prion disease models. We …
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Developing Circuit-Targeting Optogenetic Strategies for Pre-Clinical Model Motor Circuitry
… trafficking and axonal transduction. It will require a systematic exploration of multiple opsins and multiple targeting strategies to achieve this goal. …
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Inflammatory Parkinson's Clinical Biomarker Profiling
… Study Rationale: This study aims to compare the immune system of Parkinson’s disease (PD) patients and their … clinical research efforts have implicated the immune system as a potential source of PD biomarker information. … the same environment. These samples will be evaluated for multiple inflammatory and immunological endpoints. We will …
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The Michael J. Fox Foundation for Parkinson's Research Earmarks $2 Million to Study Role of Inflammation in PD
January 16, 2003
… in Parkinson’s disease. Inflammation is an immune system response to injury or disease, but chronic … research. This initiative seeks to approach the issue from multiple angles, including: Evaluating the prevalence of … that enhance survival of cell grafts in the nigrostriatal system; and Exploring immune status as a biomarker of …
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The Prescott Family Initiative at The Arizona Parkinson's Disease Consortium
… pathological markers of PD in both the peripheral nervous system and the central nervous system. These studies could lead to an earlier diagnosis of … Disease Consortium is a consortium of investigators at multiple institutions throughout Arizona: Mayo Clinic …
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Caleb Webber, PhD
… may be best understood through the contribution of multiple genes to multiple disease-relevant processes. Thus, Dr. Webber does … and models of gene functional relationships that allow multiple pathways and processes to intersect. His gene …