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Eureka Aleart: Small Molecules Found to Protect Cells in Multiple Models of Parkinson's Disease
December 28, 2009
… of protecting cells from alpha-synuclein toxicity in multiple models of Parkinson's disease, according to … this research, we used yeast as a Parkinson's disease model system to identify the compounds that really work in two higher order model systems of Parkinson's," says Julie Su, a first co-author on …
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Regulated GDNF Gene Therapy: A Novel Regulatory System Based on Protein Degradation
… grant: Regulated GDNF Gene Therapy: a Novel Regulatory System Based on Protein Degradation Promising Outcomes of … step towards development of a new regulatable gene therapy system for trophic factors to combat Parkinson’s disease. … vivo. This will give us insight into the possibility of the system for dosing the gene therapy. Moreover, we will …
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Research Paper Adds Clinical Anchors to Proposed Parkinson’s Staging System
October 11, 2024
… the Neuronal alpha-Synuclein Disease Integrated Staging System (NSD-ISS) . The FDA acknowledged the potential of … fine-tune these definitions and improve the staging system even further. The NSD-ISS framework, bolstered by …
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New Findings Add to Evidence of Immune System Role in Parkinson's Disease
June 22, 2017
… University revealed a possible link between the immune system -- the body's defense system against disease -- and alpha-synuclein , the sticky … derived from alpha-synuclein are recognized by the immune system in people with PD, which could produce an autoimmune …
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Tufts Report Offers Mixed Outlook on Central Nervous System Drug Pipeline
March 13, 2012
… in general unfolds at a snail’s pace, central nervous system (CNS) drug development moves at the clip of a banana …