… earliest brain pathology of PD occurs outside of the motor system, namely in the olfactory bulbs (brain regions that …

… of protecting cells from alpha-synuclein toxicity in multiple models of Parkinson's disease, according to … this research, we used yeast as a Parkinson's disease model system to identify the compounds that really work in two higher order model systems of Parkinson's," says Julie Su, a first co-author on …

… grant: Regulated GDNF Gene Therapy: a Novel Regulatory System Based on Protein Degradation Promising Outcomes of … step towards development of a new regulatable gene therapy system for trophic factors to combat Parkinson’s disease. … vivo. This will give us insight into the possibility of the system for dosing the gene therapy. Moreover, we will …

… the Neuronal alpha-Synuclein Disease Integrated Staging System (NSD-ISS) . The FDA acknowledged the potential of … fine-tune these definitions and improve the staging system even further.  The NSD-ISS framework, bolstered by …

… University revealed a possible link between the immune system -- the body's defense system against disease -- and alpha-synuclein , the sticky … derived from alpha-synuclein are recognized by the immune system in people with PD, which could produce an autoimmune …