-
Comparing the Effectiveness of Two Imaging Methods for Monitoring the Progression of Parkinson’s Disease
… imaging methods can be used to monitor the brain’s dopamine systems and assess how dopamine-producing neurons are … study in which people with PD undergo repeated imaging at multiple time points. Such assessment could improve our …
-
Using “Nanobodies” to Prevent Formation of Intracellular Alpha-synuclein Aggregates
… particular, we will inhibit proteasomes and lysosomes, two systems cells use to degrade damaged and worn-out … its penetration and distribution. Finally, we will use multiple techniques to assess whether protection of …
-
Characterizing the Immune Cells Present in the Blood and Cerebrospinal Fluid of People with Parkinson's Disease Associated with Mutations in LRRK2
… We hypothesize that specific changes in the immune system play a role in the development and progression of PD … from individuals with varying forms of PD. We will then use multiple single-cell analytic techniques to catalog the …
-
Sridhar Vasudevan, DPhil
… innovative drug targets to address unmet needs in multiple disorders. His work has been published in leading … Research Excellence Award. Dr. Vasudevan also teaches multiple courses in pharmacology for undergraduate … and MSc students. Dr. Vasudevan is a reviewer for multiple journals and granting agencies, and he consults for …
-
Staff on the Move: Foundation’s Unique Role in Venture Philanthropy
October 7, 2013
… Venture Support.’ Karen Chen, PhD, from the Spinal Muscular Atrophy Foundation also will speak on the foundation role; …
-
Ghrelin - a Peripheral, Preclinical Biomarker for Parkinson's Disease
… cohorts, i.e. patients with diabetes mellitus type 2 and multiple sclerosis. For both conditions, ghrelin serum … potential. In addition, it is known that ghrelin acts on systems that frequently are also affected in PD … sleep, etc.). Proof of an early disturbance in the ghrelin system (evolving) PD might therefore be of future diagnostic …