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Direct Reprogramming of Functional, Induced Dopaminergic Neurons from Human Adult Somatic Cells
… state and re-establishing a functional dopaminergic system. Finally, some critical aspects of these neurons will … of disease-affected iDA neurons for studying in the dish multiple pathogenetic mechanisms of PD with relevant …
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Mapping Brain Response Patterns to Deep Brain Stimulation with FMRI
… (i.e., programmed). However, DBS programming often requires multiple clinic visits to test the large number of possible … DBS for Parkinson’s disease. The process of programming DBS systems takes numerous clinic visits, resulting in a long, …
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Developing Wiring Diagrams of the Brain-Body Connection
… the neural networks that control an example of each system. Hypothesis: Understanding the wiring diagrams that … we will study the celiac ganglion, which innervates multiple internal organs, including the esophagus, stomach, …
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Researchers Looking to Improve Diagnosis of Parkinson’s
April 4, 2016
… outside of the brain helped to inform the recently launched Systemic Synuclein Sampling Study (S4). S4 will evaluate alpha-synuclein in multiple locations (saliva, blood and spinal fluid, in …
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Neuroimmune Assay Workstream Validation
… critical assays to obtain a comprehensive picture of immune system function/dysfunction in PD will allow for … reproducible results and confidence in results obtained by multiple labs. Study Design: This coordinated study plan …
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Almira (Ellie) Chabi, MD
… International. Dr. Chabi leads programs across multiple therapeutic areas including neurology, immunology, … within Ophthalmology as well as Neuroscience leading to multiple successful NDA filings. In addition to expertise … Program and has served as a board representative in multiple companies. …