… can protect the brain from damage, as shown in multiple pre-clinical models with Parkinson's features. … strand -- the genes that control alpha-synuclein levels in multiple cell lines we would be able to devise new methods … therapeutic strategy for Parkinson's disease. The proposed systematic approach to finding genes that regulate …

… neurodegenerative pathology in pre-clinical models of multiple neurodegenerative diseases. She received her PhD in … a manuscript reviewer. She has received grant funding from multiple sources including ADRC, The Michael J. Fox …

… we will obtain simultaneous electrical recordings from multiple sites in the basal ganglia of rodents. Rodents have … have been rendered Parkinsonian. Following this activity in multiple brain structures will allow us to determine how …

… significantly. ( Read more about cognitive changes in PD. ) Researchers and doctors are currently unable to definitively … (objective measures) of cognitive changes and decline in early Parkinson's disease. The investigators, led by Daniel … and longer-term studies, but they give us a window into how and why cognitive problems develop in PD, and who …

… model. The second study will examine the effects of multiple intranasal doses of GDNF given before, at the same … of Parkinson’s Disease: GDNF cannot enter the brain after systemic administration, and the surgery to inject it …

… damaged in Parkinson's disease have new evidence that these systems become abnormal a few years before symptoms appear. … with a unique opportunity to study the brain scans at multiple times and compare the symptoms to changes in the …