… fewer and fewer dopamine terminals survive, another neuron system kicks in: the serotonin neurons. The serotonin … transmitter,” but in a non-physiological manner. Studies in multiple pre-clinical models of the disease have shown that …

… immuno-modulatory and neuroprotective effects in cell-based systems,  pre-clinical models of disease and clinical trials in multiple sclerosis and psoriasis patients.  The biological …

… have also been the driving force behind disease-model systems and the directed the therapeutic intervention … variant. We will also assess the possible role of multiple LRRK2 variants acting together to result in disease …

… Parkinson’s disease (PD). Much evidence, accumulated from multiple experimental models, has suggested that α-syn plays … supporting the true multifactorial nature of PD, as multiple causes can induce a similar outcome regarding …

… more recently motor neuron disease. He is also involved in multiple technology development projects in the areas of … ongoing in the Unit. Dr. Davies’ team also works on multiple industry projects and technology development. …

… in genetic epidemiology. Dr. Briggs is a former National Multiple Sclerosis Society postdoctoral fellow. His research has focused on multiple sclerosis (MS), another complex neurodegenerative …