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Increased Dopamine Turnover as a Manifestation of LRRK2 Mutation
… positron emission tomography (PET) to study the dopamine system in detail in people from families with different … onset; (ii) that this abnormality will affect people from multiple different families with LRRK2 mutations, …
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Gene Therapy to Restore Protein Imbalance in Parkinson's Disease
… to specific brain areas, avoiding the possible effects of systemic and chronic administration of ER stress-targeting … the brain due to their safety profile, as demonstrated in multiple clinical trials. In this project, we plan to …
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Three Questions for a Researcher with Erwan Bezard, PhD, INSERM Research Director at the Institute of Neurodegenerative Diseases (IND) in Bordeaux, France
April 8, 2013
… looking to develop new treatments for central nervous system disorders. Each of these responsibilities plays a … to know about your daily work with PD? EB: At IND, we have multiple experts from various fields all working together in …
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Top 10: What Matters to People with Parkinson’s
December 17, 2014
… used for dementia — and improved deep brain stimulation systems are ongoing. Depression in Parkinson’s, commonly … is in testing for dementia associated with Parkinson’s, and multiple studies analyzing how and why memory problems occur …
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MJFF Study Making Strides Toward Parkinson's Biomarker
April 13, 2017
… To meet this need, in 2016, MJFF launched the Systemic Synuclein Sampling Study (S4) , an observational … S4 is the first study to evaluate alpha-synuclein in multiple body fluids and tissues within the same person and …
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Alpha-Synuclein Assay Standardization LEAPS
… blood, cerebrospinal fluid and saliva has been reported by multiple scientists using a variety of analytical … that have the necessary experience and expertise to assess multiple alpha-synuclein research assays for consistency of … who developed the assay to be tested. Each team consists of multiple laboratories that will compare the performance of …