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Suresh Dheerendra, MS
… Suresh was a Clinical Program Director at Genentech leading multiple programs from entry into the clinic to late-stage …
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Development of Novel Brain-penetrant Inflammasome Inhibitors as Potential Therapeutics for Parkinson’s Disease
… Study Rationale: The immune system displays an aberrant pattern of activity in the central nervous system of people with Parkinson’s disease (PD); this pattern … Although short-term activation of the immune system can be beneficial in fighting infections or healing …
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Xiaolu Yang, PhD
… and his lab discovered a new protein quality control (PQC) system in animal cells. This system is highly effective in suppressing protein misfolding … and is mechanistically distinct from canonical PQC systems. A main research focus of his lab now is to …
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Eltoprazine for Treatment of Levodopa-induced Dyskinesias
… fewer and fewer dopamine terminals survive, another neuron system kicks in: the serotonin neurons. The serotonin … transmitter,” but in a non-physiological manner. Studies in multiple pre-clinical models of the disease have shown that …
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An Energizing Experience: Recapping the Movement Disorder Society’s (MDS) International Congress
July 9, 2012
… it. But now we see it affects so much more than the motor system,” he says. He also noted how much the field of … and people want our opinion.” Having attended the congress multiple times before, Maurizio had already made a number of …
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Update on Alpha-synuclein Therapies in Clinical Trials
July 10, 2017
… . Harnessing the Power of the Immune System to Protect Cells AFFiRiS aims to harness the body's … This information is useful as this therapy may require multiple doses. Preventing Toxic Protein Clumps Neuropore is …