… The Brio Neurostimulation System consists of a pacemaker-like device implanted in the … disease and essential tremor. The Brio Neurostimulation System from St. Jude Medical works in a similar way as the … device: Medtronic’s Activa Deep Brain Stimulation Therapy System, approved in 1997 for tremor and in 2002 for …

… explained, research indicates that Parkinson’s may involve multiple systems in the body beyond the central nervous system, and it may affect these systems before the motor …

… death of nerves within the gut (i.e., the enteric nervous system), driven by accumulation of toxic forms of the … symptoms. This program seeks to develop a new experimental system that accurately replicates Parkinson’s disease biology in enteric nervous system cell cultures. The investigators will use it to …

… Objective/Rationale: The glutamate, serotonin and adenosine systems are interesting targets for pharmacological … disease. However, interventions addressed at single systems have so far produced limited results. Indeed, the … are complex and affect the function of several brain systems. In this project we intend to counteract dyskinesia …

… killer (NK) cells play a protective role on the nervous system in Parkinson’s disease. We evaluated the role of NK … cells in synuclein-related diseases that affect the nervous system. Our study provided evidence of potential usefulness … demonstrated the protective role of NK cells on the nervous system in a preclinical model of Parkinson’s. The next steps …

… statistical analysis of large epidemiological cohorts, with multiple, correlated and error-prone factors of disease. She …