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Studying DNA Methylation in Parkinson’s Disease Using the Systemic Synuclein Sampling Study
… symptom progression. We propose using the samples from the Systemic Synuclein Sampling Study (S4) to identify … levels in different tissues and to responses of biologic systems in PD via metabolomics. Impact on …
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Tufts Report Offers Mixed Outlook on Central Nervous System Drug Pipeline
March 13, 2012
… in general unfolds at a snail’s pace, central nervous system (CNS) drug development moves at the clip of a banana …
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The Michael J. Fox Foundation Funds $2 Million to Solve Midbrain System Mysteries
June 23, 2004
… signals that produce and maintain the midbrain dopaminergic system that degenerates in Parkinson’s disease. The awards … Patterning and Maintenance of Midbrain Dopaminergic Systems in the Normal and Parkinsonian Brain initiative: …
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Clinical Evaluation of LRRK2 Inhibitors on Inflammatory Responses in Crohn's and Parkinson's Diseases
… in CD and PD. … LRRK2 … Inflammation … LRRK2 in the Immune System … Tsuneya Ikezu, MD//PhD …
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Axonopathy induced by overexpression of human -synuclein in the rat nigrostriatal dopamine system
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Assessment of the Novel Neuronal Synuclein Disease Staging System in Stratifying Dementia with Lewy Bodies Patients
… of "the neuronal synuclein disease (NSD) integrated staging system,” originally designed for PD, in people with … translational research on DLB. We will use the NSD staging system to categorize patients within the E-DLB that have …